a part that forms when you tie a piece of rope, string, fabric, etc., to itself or to something else
a part where something has become twisted or wrapped around itself —often used figuratively
a painful or uncomfortable feeling of tightness in part of your body
2knotverb
to tie a section of rope, string, fabric, etc., to itself or to something else so that a knot forms : to make a knot in (something); also : to connect (two or more parts or things) with a knot
to develop a painful or uncomfortable feeling of tightness—often + up